Dried Kratom (Mitragyna speciosa) is a tropical tree native to the forests of Southeast Asia. It has been used by people in Thailand, Malaysia and Indonesia for centuries to increase the resilience of manual labor. Unlike many herbal remedies, the active ingredient of Kratom, mitragynine and 7-OH-mitragynine has been identified and characterized. Both chemical compounds associated with yohimbine, but bind to receptors mu, delta and kappa opiate in the body and brain (mu opiate receptor underlying fun and addictive effects of opiates such as morphine and heroin).
Previously unknown in the West, it is becoming increasingly popular because of the internet activity of retailers, many of whom advertise as a “legal high”. While this is true, Kratom has many legitimate uses apart from poisoning and has great potential as an alternative medicine to treat some very difficult to manage the condition.
Effect: In low doses, Kratom seems like a stimulant, providing additional energy and endurance. It is in high doses Kratom is the opium-like effects become apparent and user experience sedation, nausea and euphoria. Because the binding affinity to opiate receptors throughout the body, including the brain, Kratom’s effects are similar to many opiate analgesics, including codeine and morphine. It produces intoxication state similar to Opium and can be habit forming, although in a less intense way. The side effects of opiates and may also be present, including itching and constipation.
Dosage: The power of Kratom is highly variable depending on the strain, suppliers, and the time of year. Low doses varying from 2-4 grams and high doses ranged from 5-10 grams. Doses higher than 10 grams, especially high grade Kratom always cause side effects including nausea, vomiting and agitation motors. Overdose and death have not been recorded with Kratom itself although it was detected in the blood of at least at least one polydrug deaths in Asia involving the whole cocktail of other harmful substances.
How to consumption: there are various methods of consuming or extracting Kratom can be obtained in a variety of forms, including whole leaf, crushed leaves and as a powder. The powder form is easy to handle and will produce the greatest effect for the least amount of effort.
The simplest method of taking kratom will just swallow the powder dry. This can be done relatively painlessly by pouring a little water in the mouth, tilt the head back so that the water covers the throat, disposal in a number of pre-measured Kratom from a piece of paper folded half and swallow. If done correctly eater Kratom Kratom may not even taste.
Eating dried Kratom delay onset of effect and prolong their duration. For a faster onset, Kratom can be boiled briefly in boiling water and then consumed as a tea. Due to the low solubility of the active alkaloid in water, it is recommended that the plant material can be consumed with tea rather than filtered out.
Extract: Alkaloids in Kratom, including mitragynine and 7-OH-mitragynine is not easily soluble in water, but can be extracted with other solvents. However, the effects of Kratom seems to be mediated by a variety of different kinds of alkaloids and it is for this reason that the extract, sometimes labeled X 10, 30 X 100 X or even often less powerful than along 1X plain leaf although one reported case of lethal overdose in Thailand involved Kratom extract in combination with other drugs are very powerful.
Drug benefits and effects Heath: Kratom has been used in traditional Thailand to treat diarrhea and studies in mice demonstrated to be effective as Loperimide (Immodium AD) primarily for the treatment of severe diarrhea (Chittrakarn, 2007).
More recently, chronic opiate users have started using Kratom for the treatment of opiate withdrawal (Vicknasingam, 2010). In most cases, Kratom can completely replace the opiate abuse and reduce withdrawal symptoms even in very severe opiate like heroin addicts IV users. Kratom itself can cause physical dependance but withdrawal symptoms are no where near as severe as that is illegal or prescription opiates and many addicts have found it useful to convert their addiction to the first Kratom before stopping altogether.
Because the biological similarity to opiate analgesics, Kratom can be successfully used as an alternative for moderate to severe pain. That’s less than the habit-forming drugs such as oxycodone, morphine or hydrocodone which is traditionally used to treat conditions such as chronic back pain, and may be just as effective.
Anecdotal evidence indicates that Kratom may be useful in reducing the symptoms restles foot syndrome (RLS Sol) although once accustomed, withdrawal symptoms can make the condition worse while.
Some of the compounds found in dried Kratom leaves has been shown to have antioxidant properties and is therefore considered a significant health benefits. In addition, consumption of Kratom can help add fiber digestive tract.
Endorsement: Kratom completely legal in most of the West, including the United States and Canada. It is illegal to possess or sell in Thailand, Malaysia, or Australia but legal in Indonesia where most of Kratom in western markets originated. It is not approved for human consumption by the FDA in the United States or the relevant agencies in Canada and for this reason are not heavily marketed on a large scale.
Source: Kratom can be purchased in large quantities directly from farmers, but most customers in the USA and Canada opted for personal use Kratom number of orders from the leading vendors in their own country. Wisdom is recommended when buying Kratom because of unscrupulous online retailers who sell Kratom sub-par or even dangerous to consume false.
Most Canadian customers purchasing from the US site but more stores Kratom from Canada, as madamkratom.ca, have emerged and offer lower shipping costs, faster delivery and competitive price. However, many customers continue to order from American sources due to lack of information or the perceived value of more than US sites.
Conclusion: Long only “legal high” like Salvia, Kratom offers many health benefits for those who are interested in alternative medicines and possible major boon to those who fought against opium dependency. While it is still largely unknown in the West, it is slowly becoming more popular and easily available online.
Reference: Chittrakarn S, Sawangjaroen K, Prasettho S, Janchawee B, Keawpradub N. Inhibitory effects of kratom leaf extract (Mitragyna speciosa Korth.) In the gastrointestinal tract of mice. J Ethnopharmacol. 2008 February 28; 116 (1): 173-8. EPub 2007 November 28.
Balasingam Vicknasingama, Suresh Narayananb, Goh Teik BA, Sharif Mahsufi informal Mansora ketum use (Mitragyna speciosa) for opioid withdrawal in the northern states of peninsular Malaysia and implications for drug replacement therapy. International journal of drug policy 21283-288 (2010)
Wichian Tungtananuwat and Somsong Lawanprasert. Fatal 4 x 100; Kratom artificial juice cocktail. J Health Res 2010, 24 (1): 43-47